A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Science of Tears and Emotion
The Start of Brain Research
So Lydia Cassone said that they all went back to their respective scientists and asked what on earth this had to do with memory. And do you know that since about the late 1960s and early 1970s we have learned more about the mind, more about the subconscious mind, more about the body, more about the mind/body connection than in any previous 2000 years in our history. Look at just what we’ve learned.
Genome and Proteins
Look at the genome stuff that we’ve learned. Do you know that proteins are being investigated. They say that there are 6 million proteins in the body and when we know all the proteins in the body, we will be able to cure anything in humans. It’s frightening isn’t it, but that’s where it’s going. We’ve learned a lot in the last 40 or so years.
Tears – a Different Chemical Composition
One of the things that we’ve learned, I use in seminars and I think it’s really interesting. You know tears that we have. We can have tears of sadness and we can also have tears of happiness. Well do you know that they have a different chemical composition? So in other words we’re doing something different to our body when we have tears of sadness and tears of joy. Now that coupled with another research scientist, Rappaport, is fantastic information.
Emotion is Memory for the Subconscious Mind
You see, Rappaport showed emotion is memory for the subconscious mind. Emotion is memory and this was proved in 1971. What was actually proved was that emotion is not only involved with memory, it is the very basis on which memory takes place.
A Quick Demonstration
Now, when you think about that, a quick demonstration is that you could go back in your mind right now to something that you didn’t like – something that was an adversity, a trauma ….. OK, no need to go any further as you’ve probably got it already. Don’t think about it any more. But you go there easily, you know what the occasion was, you know what hurt – all that sort of thing.
Another Demonstration
And I could also ask you to go back to a really fantastic event in your life. You might for example go back to when you were riding your two-wheeler bike for the first time, or maybe your first kiss, or maybe a fantastic result at sport or in school, or something like that. We have so many good, joyous occasions in our mind and they will come up.
How Did You Remember
Now, how did you remember them? That’s the key – how did you remember them? To remember either the negative event or the joyous event, did you have to tell other people about it? Did you have to write about it again and again? Did you have to make a mind map about it? Did you have to do all those sorts of things to remember it? No, it just stuck fast didn’t it. It’s right there. So, in other words, the emotion of the event made it stay in your memory.
Remembering With Only Positive Emotion
So now, if we can remember with both negative emotion and positive emotion, do we use negative emotion to enhance imprinting on our memory? The answer is no, because of the tear stuff. Tears of sadness, tears of joy – different chemical constitution. We know we’re doing something different to our body with negative stuff and the negative stuff doesn’t make us feel good. So therefore we only use positive, joyous memory connections to enhance memory within the subconscious mind. So that’s something that came out of this science a long time ago.
By Sandy MacGregor – http://www.selfimprovementdeals.com
See it on Video – 08 of 16 Science of Tears and Emotion
Next Video – 09 Sandy's Trauma and Beginning of Grief
Today Finnair begins flying direct to Chongqing, one of the largest and fastest-growing cities in China. The new route is a logical next step in the carrier’s strategy of offering the shortest connections between Asia and Europe via Helsinki. Finnair is the first carrier to open a direct flight route between Europe and Chongqing.
Besides booming business activity, Chongqing offers much to see for tourists interested in China’s history and nature. Visitors can enjoy historical buildings, temples, hot springs and natural beauty, as well as the Dazu Rock Carvings, a UNESCO World Heritage Site. Chongqing also provides convenient access to river cruises on the Jialing and Yangtze rivers, and the city is well connected to Lhasa, Xian and Kunming.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/finnair/53815
A juicy, incisive exploration of gossip in all its forms. From celebrity rumors to literary romans a clef, from personal sniping to political slander, by one our great essayists, David Brooks. Learn more about this book here, http://bit.ly/qg0Sx5 and its author here, http://bit.ly/rihGG4 Non-Fiction
Just 18 weeks after Racine Reads: Dream Big! launched, Racine elementary school students have one million reasons to celebrate after reaching the program’s ambitious goal to read one million books during the 2011-2012 school year. More than 10,000 students in nearly 500 classrooms participated in the community-based initiative which aimed to get the community fired up and focused on one issue — literacy.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54460-racine-reads-dream-big-program-goal-achieved
In conjunction with the launch of its new super-capacity Door-in-Door™ French-door refrigerator, LG Electronics USA announced consumer survey results that show Americans have a short list of “go-to” foods and beverages that are consistently used on a daily basis. Catering to consumers’ “on-the-go” lifestyle, LG’s convenient Door-in-Door™ feature consists of a compartment within one of the refrigerator doors allowing consumers easier access to everyday foods.
To view Multimedia News Release, go to http://www.multivu.com/mnr/56408-lg-electronics-introduces-innovative-door-in-door-french-door-refrigerator
Less than one year ago, the .CO domain burst onto the scene when it was launched internationally. A unique digital asset with broad, global appeal, .CO is shaking up the marketplace, with upward of one million domain names registered by entrepreneurs and innovative brands in more than 200 countries worldwide.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/prne/cointernet/48931/
Jesus Came To Save You And I Not To Condem Us. John Chapter 12 esus shouted to the crowds, if you trust me, you are really trusting God. For when you see me, you are seeing the one who sent me. I have come is the light to shine in this dark world, so that all who would put their trust in me will no longer wander in the darkness. If anyone hears me and doesn't obey me, I am not his judge -- for I have come to save the world and not to judge it. For all who reject me and my message will be judged at the day of judgment by the truths I have spoken. For these are not my own ideas, but I have told you what the father told me to tell you. And I know his instructions lead to eternal life; so whatever he tells me to say, I say.
GDF SUEZ Energy Resources NA, one of the largest competitive retail electricity providers to commercial, industrial, and institutional customers in the country, announced the launch of a complimentary, mobile-optimized application designed to give energy buyers direct access to historical electricity pricing data through smartphones and similar devices.
The app, which is available for download at www.gdfsuezapps.com, provides users with easy access to data that can help them make more informed energy management decisions by instantly delivering a wide range of historical pricing. By entering a specific territory or zone, buyers can view daily, weekly, and monthly historical pricing trends for both real-time and day-ahead energy for PJM, NYISO, ERCOT, MISO, and ISO-New England.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/gdfsuezenergyresources/50486/
The tile of this post My Goals For Today- How Did I Do is something that might have caught your eyes. One of my goals for today was to sort out 1 box of 7 that I need to file away. How did I do you make be thinking or want to ask. Well I didn’t get to it. It seemed like I was easily distracted and could get it done. My mind felt like it was racing all day and I was not focused. I am to the place now where I am thinking there is something wrong with me.
I didn’t get where I am now professionally by nothing but proving myself. I know I have it in me to accomplish the things I need to get done. So I am going to come up with a new game plan and I will be sharing that with you in the near future. I am really frustrated and aggravated right now.
Tomorrow and this weekend is a new start for me. I am realizing I lack motivation. I realize now more then anything I am my own worse enemy.
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