A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
www.Clicktecs.com The digital world has permeated every aspect of our daily lives, from the way we spend our time, to the way we spend our money. It has changed the way we communicate, and it has really changed the way we seek and receive information.
Businesses are recognizing this shift from offline media to online media, and realizing that in order to acquire leads, build targeted traffic and convert more customers in the new normal, they have to start measuring different metrics.
Some companies have started testing SEO, and others may be doing some Social Media. If you are publishing content, then you may unknowingly be doing content marketing. These three commonly used marketing tactics, when executed together on a consistent basis can produce some really great results and it is what smart marketers have figured out. Conveniently named \'Optimized Content Marketing\'.
Today, WebMD released In Their Own Words: Moving Beyond Migraine with Robin Roberts, a new five-part video series that sheds light on the debilitating nature of migraine and the impact it has on all aspects of a sufferer’s personal and professional life.
To learn more about treatments and the individuals featured in In Their Own Words: Moving Beyond Migraine with Robin Roberts, visit: to www.webmd.com/insidemigraines.
Moving Beyond Migraine follows the lives of Jennifer, a public school administrator who has lived with intense migraine headaches for over 20 years; Kate, a 20-year-old college student with debilitating migraines that have run in her family for generations; Melanie, whose intense migraine condition has altered the dynamics of her nine year marriage; and Lynn, who after suffering from migraine for 50 years, shares how a clinical trial for a new treatment called CGRP targeted therapy is finally providing her with some relief.
To view the multimedia release go to:
https://www.multivu.com/players/English/7579759-robin-roberts-moving-beyond-migraine/
The Ad Council is joining forces with BAM! Body and Mind and KIDZ BOP to premiere The Greatest Action Movie Ever (G.A.M.E), a kid-targeted film offering fun ways to channel the inner action hero and take steps towards a more active and nutritionally-balanced lifestyle. Starring Ryan Ochoa of the hit Disney XD series Pair of Kings, the first half of the six-minute long G.A.M.E. film will premiere on Sunday, April 14 on Disney XD as part of Disney’s Magic of Healthy Living, an initiative that inspires kids and families to lead healthier lifestyles. Audiences will then be directed to Centers for Disease Control and Prevention’s BAM! Body and Mind website, BAM.gov, to see the second part of the film and access additional health-related resources. The full-length film will also be featured on KIDZBOP.com and Disney.com.
To view Multimedia News Release, go to http://www.multivu.com/mnr/61182-ad-council-mccann-bam-kidz-bop-help-fight-childhood-obesity
Tesla has unveiled its highly anticipated Model 3 electric car.
Customers have been looking forward to a lower-cost way to buy one of the California-based company's products, while investors hope it will swing the company from loss to profit.
But other more established automakers are launching electric vehicles of their own targeted at the same market.
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The American Civil Liberties Union today released a new video condemning the U.S. government practice of issuing death sentences without due process as part of its targeted killing policy. “Targeted Killing” is being released to coincide with the filing today of an unprecedented lawsuit by the ACLU and the Center for Constitutional Rights (CCR) challenging the government's asserted authority to use lethal force against U.S. citizens located far from any battlefield without judicial process, and without disclosing the standards it uses to target individuals for death.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/aclu/39479/
The National Insurance Crime Bureau (NICB) today warned drivers in the Las Vegas area to be on the lookout for criminals targeting trucks in a deliberate attempt to cause an accident for the purpose of collecting insurance money.
As many as 100 suspected staged accidents along the I-15 corridor through the metropolitan Las Vegas area have been reported to NICB in the past 12-18 months and as many as 25 of those accidents targeted big rig trucks. The NICB is working closely with its member companies, the Nevada Insurance Council, the Nevada Highway Patrol, and the Nevada Attorney General’s Office to track down the organizers behind these schemes.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53844-nicb-staged-accidents-targeting-big-rig-trucks-could-turn-deadly
National Association for Latino Community Asset Builders announced today that they have invested a total of 137 million dollars into predominantly Latino communities that have been hard hit by foreclosures. This effort has successfully restored neighborhoods and stabilized communities in eight states and the District of Columbia.
The initial investment of funds came from a grant from the U.S. Department of Housing and Urban Development and is the largest grant ever targeted by the federal government to predominantly Latino communities.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58956-cplc-nalcab-invest-in-foreclosure-hit-latino-communities-hud-grant
Promotional Products Work! Week, February 25 through March 1, 2013, sponsored by Promotional Products Association International (PPAI), the world’s largest and oldest international not-for-profit promotional products association founded in 1903, is an industry event dedicated to demonstrating the importance of promotional products as a powerful and effective advertising medium. A new study released by PPAI this week, The Influence of Promotional Products on Consumer Behavior, demonstrates that advertisers and marketers, now more than ever, can look to promotional products to deliver the highest rate of reach, recall and return on investment in the advertising industry, as the most cost-effective way to impact a targeted audience in a tangible, long-lasting and memorable manner.
To view Multimedia News Release, go to http://www.multivu.com/mnr/60314-ppai-celebrates-promotional-products-work-week
Children International, a U.S.-based humanitarian organization, has seen that comprehensive, targeted programs provided in a caring environment empower youth to escape the traps of poverty. The organization’s 2012 Youth Report explains how.
More than one-third of the world’s population, nearly 2.5 billion people, live on less than US $2 a day according to The World Bank. Employment can be life-changing for these people, but poverty is a hard trap to escape when it is all you know. Children International’s comprehensive youth programs provide young people with thoughtfully designed tools and experiences that can open doors to a life beyond poverty.
To view Multimedia News Release, go to http://www.multivu.com/mnr/57993-children-international-2012-youth-report-escape-poverty-find-employment
Researchers studying the genetic roots of the most common malignant childhood brain tumor have discovered missteps in three of the four subtypes of the cancer that involve genes already targeted for drug development.
