A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
http://www.dualfit.com - Follow DualFIT expert trainer Steve Pfiester through this basic yoga workout. Repeat the complete sequence 2-3 times, as well as hold each pose for more breaths, for a more challenging yoga session
http://www.globalintegra.com/blog/ This video answers the question what is competitor analysis with an interesting analogy from The Godfather.
Most businesses should do some form of competitor analysis or the other, be it seo competitor analysis, website competitor analysis or marketing competitor analysis. It is only then that a business can asses its stand in the market. Moreover, a lot of things can be learnt from competitors. It does not take much to conduct competitor analysis, a basic form of it is possible through mere observation.
This video talks about the importance of competitor analysis and why every business should adopt some form of it or the other.
When it comes to their health, nearly 90 percent of Americans lack the literacy skills to understand basic medical information and instruction. Low literacy has been linked to poor health outcomes such as higher rates of hospitalization and less frequent use of preventive services. A few quick minutes with a physician is not sufficient for most of us to understand a complex or chronic medical condition and how we can manage it. But new research indicates that video storytelling can be an effective way to educate people about health conditions - and watching others share their health stories can empower people to take control of their own health.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/besmartbewell/50819/
As wars end, the hardship continues. Servicemen are still stationed overseas, families remain left behind and veterans return to an economy stuck in the doldrums. The Veterans of Foreign Wars Foundation’s Return the Favor campaign supports programs and services that work to ease the burden on America’s active-duty military, veterans and their families.
One key part of the campaign is the Unmet Needs Program. The program assists with basic life needs such as rent, mortgage, utilities, vehicle repair, medical expenses or food/basic assistance. It has helped over 3,000 military families and funds are available to all five branches of the military, as well as members of the National Guard and Reserves. Since 2004, the Unmet Needs Program has provided more than $4 million dollars in financial assistance to deserving military families.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53538-vfw-foundation-return-the-favor-campaign-on-national-tv-series-giving-back
Twenty-two vehicles earn the Insurance Institute for Highway Safety's highest safety award for 2014, TOP SAFETY PICK+, thanks to a high level of protection in crashes and the availability of front crash prevention technology to avoid many collisions in the first place. An additional 17 earn TOP SAFETY PICK by meeting the crashworthiness criteria alone.
IIHS is using new criteria for the awards this year. TOP SAFETY PICK requires good performance in the Institute's moderate overlap front, side, roof strength and head restraint tests and, for the first time, good or acceptable performance in the small overlap front test introduced in 2012. The same level of performance in those tests, along with at least a basic rating for front crash prevention, is required for the higher accolade, TOP SAFETY PICK+.
UNICEF - Put It Right (http://bit.ly/do5things) is a 5 year initiative by UNICEF UK to inspire action to protect the rights of children everywhere. This film is a window into the world of children around the world who are missing out on these basic rights - the rights to learn, to clean water, to be healthy, to be looked after and just to be a child. The film shows their extraordinary resilience in tough times, but the question is simple -- Is this right?
Radiohead donated their track 'Videotape' to the film.
Toastmasters International, the world’s largest non-profit organization dedicated to teaching public speaking and leadership skills, is launching a video series of time-tested tips for improving communication. The first two videos to debut are basic public speaking and job interview tips.
“Every day a quarter of a million people attend Toastmasters meetings, seeking to become more confident speakers and leaders. These videos give anyone, not only members, access to Toastmasters time-tested tips they can use immediately,” says Toastmasters International President Michael Notaro.
To view Multimedia News Release, go to http://www.multivu.com/mnr/49430-toasmasters-communication-challenges-time-tested-tips-public-speaking
In this new video from EisnerAmper, one of the nation’s leading providers of employee retirement plan audits, partner Kriste DeAngelo presents a basic outline for how Benefit Plan Administrators should take extra care to avoid late filing of Employee Retirement Plan contributions, or remittances. View EisnerAmper’s newest video at http://www.multivu.com/players/English/7461932-eisneramperemployee-benefits/ DeAngelo, who is the lead engagement partner for over 50 retirement plan clients, says there are three steps all plan professionals should take at the outset
Determine the earliest date that your company can reasonably segregate participant deferrals from the general assets of the company and remit into the Plan, and document the company’s remittance process. 2. Follow what has been documented. 3. Check the remittance data throughout the year – this is crucial. According to DeAngelo, “Anything outside of the expected time frame could be considered a late remittance by the DOL and should be voluntarily corrected.” DeAngelo goes on to say that many benefit managers stumble on the perception that, according to the DOL, retirement plan remittances must be made “no later than the 15th business day of the following month.”
To view the multimedia release visit:
http://www.multivu.com/players/English/7461932-eisneramper-employee-benefits/
Texas Instruments (TI) today announced the TI-Innovator™ Rover, the company’s first robotics solution for middle and high school students that makes learning STEM subjects a moving experience. Students can write programs on their TI graphing calculators that get Rover’s wheels turning and their minds learning in a fun, interactive and hands-on way.
Rover connects to the TI-Innovator Hub and either a TI-84 Plus CE or TI-Nspire™ CX graphing calculator that many students already have and drives interest and curiosity in science, technology, engineering and math (STEM) subjects. Students without any exposure to coding or robotics can get started by writing a basic program to make Rover do things like draw, dance or even crash.
To view the multimedia release go to:
https://www.multivu.com/players/English/7746259-ti-introduces-ti-innovator-rover-robot/
Written by Paul Val. http://www.valmusic.com Performed by Uppercut featuring Brent Carter, This song was written in response to the Columbine school massacre that took place on April 20, 1999. It addresses some of the basic changes in our Traditional American Values that may have contributed to this tragedy and that continue to erode our values and put all of us in harms way.
Black Rose Productions Inc.
