A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
In the 1960’s, Richard O’Barry was the world’s leading authority on dolphin training, working on the set of the popular television program Flipper. Day in and day out, O’Barry kept the dolphins working and television audiences smiling. But one day, that all came to a tragic end. THE COVE, directed by Louie Psihoyos, tells the amazing true story of how Psihoyos, O’Barry and an elite team of activists, filmmakers and freedivers embarked on a covert mission to penetrate a hidden cove in Japan, shining light on a dark and deadly secret. The mysteries they uncovere ...
http://www.thecovemovieuk.com/thecove.html
Recent unfounded statements surrounding the safety of wheelchair accessible vehicle conversions has caused industry organizations to rally in an effort to set the record straight. The National Mobility Equipment Dealers Association (NMEDA) and several of its manufacturing members announced today their position on the recent allegations.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54214-braunability-disability-organizations-react-to-misleading-statements
Grilling season is in full swing, but the same old menu of burgers, hot dogs and macaroni salad could use some fresh ingredients and ideas. Whether you have a home garden or a local farmers’ market, summer brings an abundance of fruits and vegetables that are prime for grilling. In celebration of its 70th anniversary year, Organic Gardening magazine is keeping the season festive with recipes that take the garden to the grill.
Produce is the tastiest and most nutrient-dense when it is in-season, and it can be more affordable too. Grilling brings out the flavors and juices in fruits and vegetables: corn and zucchini take on a delicious, smoky flavor and the natural sugars in peaches and pineapple caramelize to perfection. Not sure where to begin? Organic Gardening’s Consulting Food and Wine Editor Victoria von Biel offers tips for a more flavorful grilling season.
To view Multimedia News Release, go to http://www.multivu.com/mnr/53919-organic-gardening-magazine-70-th-anniversary-recipes-from-garden-to-grill
