A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
http://www.youtube.com/watch?v=_rW53gM_4yw[EXTRACT]
http://www.shopping-cart-migration.com/Cart2Cart is an automated online service designed to help you migrate your products, customers and order history from your existing shopping cart to the dream eCommerce platform, such as Magento, PrestaShop, CS-Cart, VirtueMart, etc. with: - No programming skills necessary, - No software to install, - FREE Demo Migration available, In this video tutorial you will find out how to install connection bridge on your Source Shopping Cart for fast and easy store migration with Cart2Cart. start your Shopping Cart Migration right away at http://www.shopping-cart-migration.com
In the mountains of Nepal…in a remote monastery, Buddhist monks inexplicably turn to cannibalism and torture – while Painter Crowe, director of Sigma Force, begins to show signs of the same baffling, mind-destroying malady…and Lisa Cummings, a dedicated American doctor, becomes the target of a brutal, clandestine assassin. Learn about the author here http://bit.ly/JamesRollins3 Learn about the book here http://bit.ly/BlackOrder Thriller, Suspense, Mystery
On the 11th of November, Nordic hotel chain Scandic’s new lifestyle venture, Scandic Grand Central in the city center of Stockholm, Sweden, held its opening party. The hotel is the result of the hotel chain’s new drive to attract more international travelers and attract new target groups.
The hotel has 391 rooms, conference facilities, gym, restaurant, bistro and a large hotel bar/lounge open to the public. Scandic’s ambition is to develop unpretentious yet innovative hotels that are considerate of the environment as well as compassionate. Scandic Grand Central will be infused with Stockholm’s ‘downtown’ street culture and its vibrant atmosphere.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52789-scandichotels
New findings from the St. Jude Children’s Research Hospital – Washington University Pediatric Cancer Genome Project (PCGP) have helped identify the mechanism that makes the childhood eye tumor retinoblastoma so aggressive. The discovery explains why the tumor develops so rapidly while other cancers can take years or even decades to form.
The finding also led investigators to a new treatment target and possible therapy for the rare childhood tumor of the retina, the light-sensing tissue at the back of the eye. The study appears in the January 11 advance online edition of the scientific journal Nature.
To view Multimedia News Release, go to http://www.multivu.com/mnr/46767-st-jude-genome-project-treatment-childhood-eye-tumor-retinoblastoma
Bianor today announced a partnership with PR Newswire, the global leader of marketing and communications solutions, bringing PR Newswire’s customers’ multimedia news content directly to their connected devices, including internet TV and gaming consoles via Bianor’s iMediaShare application.
Bianor’s iMediaShare, the complete end-to-end push-to-TV platform, represents a great opportunity for users of PR Newswire’s broadcast and multimedia services, offering the interactive consumer the invaluable ability to access on-demand news content on a television, engaging their target audiences in a more dynamic way.
To view Multimedia News Release, go to http://www.multivu.com/mnr/55187-pr-newswire-bianor-deliver-on-demand-video-content-imediashare
http://www.youtube.com/watch?v=njxTe1NQA2o Keeping kids safe while they\'re online is a moving target. Here are some tips that will help. http://thebesthomesecurity.org/internet-safety-tips-to-protect-your-kids-online/
http://fitnessweightlosscenter.com - Squat Exercise | Leg Workouts - The squat exercise, or as most people refer to it as "squats", is probably the best single workout you can do for your legs. Squats workout your quadriceps, hamstrings and all the other muscles in your legs. You will get the most out of your squat workouts if you use free weights rather than a squat machine.
Using free weights makes you use all the little stabilizer muscles in your legs and adds to the effectiveness of the exercise. Just make sure not to get so infatuated with squats that you ignore the other exercises that target you legs. And remember that working out your legs is just as beneficial as working on your chest and arms and maybe more so. Strong and powerful legs provide a strong base for any other training or athletics.
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PR Newswire, the leading global provider of innovative marketing and communications solutions, today unveiled Agility, the first fully integrated communications and workflow platform to combine powerful media monitoring, media targeting and real-time engagement tools with industry-leading content distribution capabilities—all from a single dashboard.
Agility, which currently has more than 300 active early adopters, allows marketing and communications professionals to free themselves from the disparate platforms they currently use, and now seamlessly target, engage with and monitor traditional media and social influencers through one integrated dashboard with a single login. Agility helps these professionals glean actionable insights into who is saying what about their brand, how influential these people are, where these conversations are happening and to engage these influencers in real-time.
To view Multimedia News Release, go to http://www.multivu.com/players/English/56537-prnewswire-agility/
This week is National Save for Retirement Week, a time for employees to reflect on their personal retirement goals and determine if they are on target to reach them. ADP® Retirement Services provides the resources, materials and online tools employees need to prepare for their financial future. In the spirit of this week, ADP Retirement Services is offering tips to save for retirement and make planning for the future as simple as possible.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58561-adp-retirement-savings-tips-during-national-save-for-retirement-week
The bayou called to him and so did she. But the bayou is as dangerous as it is sensuous and his leopard fights for control as the woman he loves becomes the target of terror. Mystery, suspense, romance and passion are all Leopard’s Prey. Christine Feehan book trailer. http://www.christinefeehan.com paranormal romance
