A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
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An early crop of advanced crash avoidance technologies includes some clear success stories when it comes to preventing crashes, insurance claim analyses by the Highway Loss Data Institute (HLDI) show.
Forward collision avoidance systems, particularly those that can brake autonomously, along with adaptive headlights, which shift direction as the driver steers, show the biggest crash reductions. Lane departure warning appears to hurt, rather than help, though it’s not clear why, and other systems, such as blind spot detection and park assist, aren’t showing clear effects on crash patterns yet.
HLDI analysts looked at how each feature affected claim frequency under a variety of insurance coverages for damage and injuries. Clear patterns were seen in claims under property damage liability (PDL) insurance, which covers damage caused by the insured vehicle to another vehicle, and collision insurance, which covers damage to the insured vehicle. Frequency is measured as the number of claims relative to the number of insured vehicle years. An insured vehicle year is one vehicle insured for one year, two vehicles for six months, etc. The model years of the vehicles included ranged from 2000 to 2011, depending on when an automaker introduced a feature. Insurance data through August 2011 were used.
http://debbiewilliamsassociates.co.uk/ditch_the_dairy.htm Chrones disease and ulcerated colitis. My mother suffered for over 35 plus years with this and had a colostomy bag as well after a spell in hospital in an unrelated illness she was in a coma for 9 days and when she came home through dietary changes she stopped suffering. Debbie changed her diet getting all dairy products out from cheese to pizza to cream cakes and milk . This stopped the pain as you will see in the video her mothers response when given some custard in the hospital how the pain came on very suddenly. Debbie herself steers clear of dairy as it seems to cause her to feel blocked up and other unpleasant side effects. Many people are lactose intolerant without realizing it and suffer low level discomfort from irritable bowel to cramping pains not knowing that dairy products may be causing this.Creating a meal plan for a couple of weeks and then gradually adding in one dairy based food at a time will let you know whether its a problem for you or not. Debbie's mother was able to have the occasional cream cake once a week and her body could handle it but after 6 years of following eating foods that Debbie prepared she started buying lots of junk food and eating out more often with cream cakes everyday the downfall was dramatic and despite Debbie trying to stop her this time as she had a new baby to contend with Olive went downhill fast and was dead within 6 months.There is a saying we are digging our graves with out teeth, the link above takes you to a hypnosis product ditch the dairy if you feel you are addicted to dairy foods and need help to get them out to test if this will help you. Also check out www.notmilkman.com where there are tons and tons of scientific references linking dairy to all sorts of diseases. Also if you would like to have a free hypnosis recording my 'Stop worrying and create a wonderful life will help you. You can get it free from here:http://www.debbiewilliamsassociates.co.uk/. Back to the top:http://www.youtube.com/my_videos_edit?ns=1&video_id=0NU5jAiSWuA
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It is slaughter on The Strip as Eli Roth’s GORETORIUM, the first year-round haunted experience to hit Las Vegas dares brave souls to enter its doors. An experience unlike any other, the 15,000-square-foot GORETORIUM, packed with state-of-the-art scares, bone-chilling special effects and a cast of hauntingly horrifying characters is now open in the heart of Sin City.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58112-eli-roth-s-goretorium-haunted-experience-las-vegas
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Aimed at children from 3-7 years of age, Gaudi Bruno is a fast-paced, exciting and interactive storybook... a beautiful introduction into nature, friendships and discovery. Unlike physical storybooks, Gaudi Bruno is fabulously interactive, allowing your child to feel as if they are exploring the world with Bruno, not just watching him.
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The June 1 start of the Atlantic hurricane season is just around the corner. Early predictions indicate an active year and the Insurance Information Institute (I.I.I.) urges the public to prepare for the heightened flood risks that come with hurricanes and tropical storms.
Flood insurance is essential to help financially protect homeowners and business owners against the devastating effects of flooding. The spring months have already brought significant flooding to many areas throughout the Midwest, such as Illinois, Indiana, Michigan, and Missouri. Also, the most recent two hurricane seasons have shown how devastating the consequences of seasonal flooding can be, with losses felt well beyond the high risk areas nearest the water.
To view Multimedia News Release, go to http://www.multivu.com/mnr/61483-floodsmart-hurricane-season-is-just-one-month-away-flood-insurance
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