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A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
On her 17th birthday, everything will change for Violet Eden. The boy she loves will betray her. Her enemy will save her. She will have to decide just how much she is willing to sacrifice. Learn more about this book here, http://bit.ly/p8li3j and its author here, http://bit.ly/qQKeWz Embrace us here, http://on.fb.me/yeeVPX YA
Once slipped angel Zachary and werewolf Kieren arrive at a mysterious boarding school, they are trapped with demon dogs, a sadistic instructor, and a fire breathing monster. Will they escape? Or will the devil have his due? Bestselling author Cynthia Leitich Smith unites heroes from the previous novels in the Tantalize series. Learn more about the book here, http://bit.ly/vVB3G0 and its author here, http://bit.ly/vcCZHi YA
Sarah Ockler’s new novel, BITTERSWEET is a story about baking, family and learning how to survive High School! Learn more about this book http://bit.ly/zhiyed Learn more about this author http://sarahockler.com/ YA
A tiempo para las fiestas de fin de año, la empresa Procter & Gamble (P&G) (NYSE: PG) trae la innovación y el beneficio de sus marcas participantes en la campaña ¿Ya Probaste Esto? para ayudar a los consumidores a verse bien, facilitar su rutina diaria y cubrir las necesidades de sus familias e invitados.
Para mas, va a http://www.multivu.com/mnr/53722-pg-have-you-tried-this-yet-clairol-nice-n-easy-color-blend-foam-martinez
Si eres como la mayoría de los consumidores, seguramente esta economía le tiene pensando sobre tu lista de compras navideñas. Sin embargo la temporada de compras Navideñas ya esta aquí, ¿y qué mejor momento que ahora para pensar en cómo puede ahorrar sin dejar de conseguir los regalos perfectos para aquellos en su lista. Experto de Estilo de Vida y Tendencias de Consumo, Reconocido Nacionalmente, Martin Amado, tiene grandes ideas para regalos que le ayudaran a estirar sus dólares esta temporada. El hablará sobre las últimas tendencias en regalos, cómo ir de compras con un presupuesto, y dará consejos sobre cómo evitar los errores más comunes mientras compra.
When silence falls, will love survive? Silence is Becca Fitzpatrick’s breathtaking continuation to the New York Times bestselling Hush, Hush Saga. Learn more about this book here, http://bit.ly/cK6Ssa and its author here, http://beccafitzpatrick.com/ YA
In Ellen Hopkins’s Perfect, the riveting companion to Impulse, four teens pursue their goals of perfection which are as different as the paths they take to get there. Everyone wants to be perfect. But what does that really mean? Only you can decide for you, what is perfect. Learn more about this book here, http://bit.ly/ruGJyX and here, TEEN.SimonandSchuster.com and its author here, http://www.ellenhopkins.com/ YA
Are you interested in writing a young adult fiction novel, but are not sure how to develop a style that appeals to young readers? This friendly guide gives you tricks of the trade and proven tips on all the steps to write a marketable YA book, from developing an idea to publishing. Learn more about this book here, http://bit.ly/nrhn9S and its author here, http://deborahhalverson.com/ Non Fiction
