A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
D Un-true Hollywood Story that Universal Studios didn’t want you to see. Deco Drive Producer, Ely Ferradas interviewed Will Ferrell during the Land of the Lost junket and
hilarity ensued. “Good skin is very important to actor Will Ferrell and he will do anything, anything to get his point across. As one intrepid yet lovely Deco producer can attest
The rich color palette and varied textures of the upcoming fall season are reflected in the first release from PANDORA’s new Autumn/Winter collection, “My Story, My Design”, which will be available in stores nationwide September 4. The initial fall release — the first of three scheduled to ship to stores through the end of December — includes hand-finished rings, earrings, pendants and charms in an array of autumn colors.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54142-pandora-autumn-winter-collection-my-story-my-design
Backyard barbecues, coolers packed for picnics, al fresco dining and hot summer days are all the ingredients for a bad case of food poisoning if you’re not careful.
Cases of foodborne illness peak during the summer months, according to the USDA. But taking a few precautions can help you avoid food poisoning, say experts featured on BeSmartBeWell.com/Food-Safety in a series of videos produced by the health and wellness website. Learn more about summertime risks and get tips to stay safe this summer—and all year long.
To view Multimedia News Release, go to https://www.multivu.com/mnr/50835-be-smart-be-well-avoid-illness-food-poisoning-this-summer
When the dark musician Jedermann gains control of the legendary Gold Baton, Tyler, his sister Christina, and their friends are drawn into a dangerous, mysterious adventure. Guided by the mythical Dr. Fuddle, these explorers journey to Orphea, saving the land from chaos and destruction, and return to earth with the gift of harmony. Get the book here-http://www.amazon.com. Find out more about the author here- http://on.fb.me/DrFuddle or read the blog! http://bit.ly/FuddleBlog Available from Story Merchant Books – http://www.storymerchant.com/books.html Dr. Fuddle and the Gold Baton by Warren Woodruff Middle Grade Fantasy
http://www.dubaicitypass.com http://www.facebook.com/dubaicitypass http://www.twitter.com/dubaicitypass Information about the Fountain: The
Dubai Fountain is a record-setting choreographed fountain system set on
the 30-acre manmade Burj Khalifa Lake, at the center of the Downtown
Dubai development in Dubai, United Arab Emirates. It was designed by
WET Design, the California-based company responsible for the fountains
at the Bellagio Hotel Lake in Las Vegas. Illuminated by 6,600 lights
and 25 colored projectors, it is 275 m (902 ft) long and shoots water
150 m (490 ft) into the air (equivalent to a 50-story building),
accompanied by a range of classical to contemporary Arabic and world
music. It was built at a cost of AED 800 million (USD 218 million) and
attracts thousands of tourists on a daily basis.
http://bit.ly/FallenAngel Passionate
as well as extreme, completely fascinating, this novel, based on a true
story, will drag you in the alternative LifeStyle universe and let you
discover an underworld made of Domination and submission. It will
insinuate your mind and catch your breath until the end, pushing the
boundaries of your imagination and desires. When Nicole --
your typical next door single mother -- logged into her account that
day, she didn't expect things to take that turn. She is approached by
the Dark One, someone that everyone in the chat room seems to fear yet
don't seem to know much about him. He will gradually take hold of her
will, bringing her through intricate paths filled with pain and
pleasures, love and anger, slowly building an intense craving in her
mind and body. But something that even He couldn't expect happened... Published by My Pouty Lips (http://www.mypoutylips.com)
Cairn Story for iPhone is a unique mobile app for adventure travelers like trekkers, hikers, bikers or skydivers and of all kind who want a better way to easily and conveniently document and share their travel experiences with friends and relatives.
http://tinyurl.com/loseweightfasttodaynow Learn the best way on how to lose weight fast and easy. I was just like you until I get this great book and follow simple steps inside. I already lose more then 10 pounds! You can read more here : http://tinyurl.com/loseweightfasttodaynow
"I Love U" is the official debut single
for singer/songwriter DeAndre Lemans which features a unique upbeat
R&B instrumental, two hot verses by rapper Ramaj Muzix, and a
solid, smooth, and soulful vocal performance by DeAndre. Based off of
the hit Web Series FREEFALL (for which "I Love U" is the Official
Season Two Theme Song), the video tells the story of the show's power
couple "Nico" (DeAndre Lemans) and "Ray" (played by actor Toni
Bernard). In the video you get to watch the couple on a downward spiral
which ultimately leads to a shocking ending. Shot and Directed with
amazing quality by Film Director Lamont Pierre, the "I Love U" music
video is definitely prepared to be a smash hit of this summer and long
time favorite to anyone that loves a good music video and a great song.
http://www.weddingstheislandway.com
Over the years of arranging and attending amazing Caribbean weddings
here on St. Thomas, we've heard so many great stories from couples as
they planned their wedding or celebrated vow renewals. We're 100%
committed to helping you create your fairytale--whatever that looks
like for you. Ask us about our wedding packages and favorite ideas to
consider for your own ceremony.
