A pill designed to zero in on abnormal genes that drive specific cancers has produced encouraging early results in children with an uncommon but aggressive type of lymphoma, as well as in children with a rare form of neuroblastoma.
A phase 1 clinical trial of the drug crizotinib achieved remissions, with minimal side effects, for 10 of the children participating in a clinical study carried out by the multicenter Children’s Oncology Group (COG). The results were “an exciting proof-of-principle” for the targeted treatment, said the study leader, Yaël P. Mossé, M.D., a pediatric oncologist at The Children’s Hospital of Philadelphia.
“We are entering a new era of cancer therapy, in which we use knowledge of basic biology to design very specific drugs that target cancer cells with potentially less side effects on healthy tissue,” said Mossé. “In addition, as we concentrate on targets in molecular pathways, we move away from an exclusive focus on one form of cancer to customizing treatments according to biological activity. Abnormal ALK activity occurs in subtypes of neuroblastoma and subtypes of lymphoma, so identifying ALK activity in individual patients may enable us to provide the most effective care.”
To view Multimedia News Release, go to http://www.multivu.com/mnr/50776-childrens-hospital-philadelphia-lymphoma-neuroblastoma-oncology-gene-trial
Virgin America, the California-based airline that is reinventing domestic travel, announces it will bring its low-fare, upscale service to Philadelphia International Airport (PHL) later this year, with tickets on sale today for three daily nonstop flights from Los Angeles International Airport (LAX) starting April 4, 2012, and two daily nonstop flights from San Francisco International Airport (SFO) starting April 10, 2012. Known for its outstanding guest service, beautifully-designed cabins and unparalleled in-flight entertainment, Virgin America has swept the major travel awards since its launch in August 2007. Most recently, the airline took top honors as “Best U.S. Airline” in both Condé Nast Traveler Readers’ Choice Awards and Travel + Leisure’s World’s Best Awards. In honor of its newest city, Virgin America is also launching a system-wide “The City of Brotherly Love: Just Got Lovelier” fare sale, with PHL-LAX fares from $129 and PHL-SFO fares from $149 (restrictions, taxes and fees applying). Tickets are available for purchase now at www.virginamerica.com and at 1.877.FLY.VIRGIN.
To view Multimedia News Release, go to http://www.multivu.com/mnr/54209-virgin-america-launches-non-stop-service-from-philadelphia
In anticipation of record data usage by the tens of thousands of visitors to this year’s national political conventions, Verizon has made significant enhancements to its network in the host cities and convention facilities.
“We know sharing the convention experience is important for visitors to Cleveland and Philadelphia so we have invested millions of dollars and worked for several years on upgrading our networks and adding capacity for these events,” said Lynn Ramsey, Vice President Network Operations – Verizon.
Enhancing the network in Cleveland, Ohio
When the Republican National Convention (RNC) arrives in Cleveland July 18-21, Verizon will have completed improvements to the city’s #1 overall network as rated by RootMetrics* in a recent Metro Rootscore® report.
To view the multimedia release go to:
http://www.multivu.com/players/English/7814951-verizon-rnc-dnc-network/
It’s the summer of 1973, and eight year-old Bobby Burke’s father has been MIA in Vietnam for three years. He’s been keeping his father alive through the magic of his SafeKeeper, a charm bracelet he wears on his wrist, but it seems lately that the SafeKeeper’s power has been fading. The military has given up hope of finding his father alive, and even Bobby’s mom has taken up with a new guy, Nick, who seems determined to become a new father to him. What’s worse, Bobby has to contend with a pair of fearsome Tolltakers who have entered his life: one, a local schoolyard bully who demands money to let Bobby get home from school in one piece; the other a demon who visits Bobby’s dreams to try to snatch the SafeKeeper from his wrist. Bobby fights desperately against these forces that seem intent on keeping his father from him forever, until his final, shattering confrontation with the truth and the understanding of the toll he must pay in order to grow up.
The Children’s Hospital of Philadelphia today announced the largest charitable donation in its history: a landmark $50 million gift from the Buerger family toward the construction of a new state-of-the-art outpatient facility. Currently under construction on the Hospital’s Main Campus in West Philadelphia, the building will be named the Buerger Center for Advanced Pediatric Care.
To view Multimedia News Release, go to http://www.multivu.com/mnr/62177-children-s-hospital-of-philadelphia-buerger-center-advanced-pediatric-care
Poor children in the Dominican Republic will now have a chance at a better life through Children International, a U.S.-based humanitarian organization, thanks to businessman Larry Phelan.
The Philadelphia attorney funded the newly inaugurated signature community center that will serve 5,000 children in the slum of La Caleta near Santo Domingo. The center will provide children access to medical and dental care, education support, and nutritional programs.
Mr. Phelan was inspired to work with Children International by his friend Dan Phelan, who funded another center in the Dominican Republic. Much like Dan’s facility, the Larry T. Phelan Community Center is state-of-the-art, with a medical clinic, dental clinic, pharmacy, library, playground, computer lab and a sports complex.
To view Multimedia News Release, go to http://www.multivu.com/mnr/52274-children-international-larry-t-phelan-community-center-la-caleta
Armando Christian Perez, also known as global music superstar Pitbull will perform LIVE at AT&T Stadium during halftime of the Dallas Cowboys game on FOX against the Philadelphia Eagles on Thanksgiving Day, Nov. 27, kicking off The Salvation Army’s annual Red Kettle Campaign. The halftime performance marks the 18th year the Dallas Cowboys have partnered with The Salvation Army to launch the campaign, which raises millions of dollars throughout the holiday season. Donations help provide meals and shelter for families, Christmas toys for millions of children, in addition to numerous other social services programs year-round such as substance abuse programs, shelter and counseling for victims of domestic violence, and military veteran assistance.
To view the Multimedia News Release, go to: http://www.multivu.com/players/English/7346051-pitbull-to-kick-off-salvation-army-red-kettle-campaign-with-halftime-performance-during-dallas-cowboys-thanksgiving-day-game/
Philadelphia remodeling is a fully licensed and insured construction services company providing management and general contracting services for all residential and commercial buildings.
After a successful pilot program in October 2009, Cancer Treatment Centers of America (CTCA) is introducing an innovative approach to cancer treatment this July at each of its four hospitals in suburban Chicago, Philadelphia, Tulsa and suburban Phoenix. Called “Patient Empowered CareSM,” this advancement in the patient treatment delivery process offers patients an average of between two and three hours with a dedicated team of specialized oncology physicians and clinicians.
To view Multimedia News Release, go to http://multivu.prnewswire.com/mnr/cancercenter/44523/
Iroko Pharmaceuticals, LLC, a Philadelphia-based pharmaceutical company focused on the development and commercialization of innovative therapeutic products, today announced the opening of its new environmentally friendly corporate headquarters in Philadelphia’s Navy Yard Corporate Center. This milestone is part of the Company’s long-term growth plan as it advances its late-stage pipeline of lower dose submicron non-steroidal anti-inflammatory drugs (NSAIDs) towards commercialization.
To view Multimedia News Release, go to http://www.multivu.com/mnr/58559-iroko-pharmaceuticals-opens-philadelphia-headquarters-hq
